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The Real Cause of Hair Loss

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The currently accepted explanation for pattern hair loss is that dihydrotestosterone (DHT) binds to hair follicles and over time this causes them to shrink until they stop producing hair. However, this explanation doesn't account for the following observations:

Are there any other holes in the DHT hypothesis? And can anyone come up with a theory that explains the observations above?

Better yet, do you know of treatments that could address these observations and reverse hair loss?

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Seems more people online are realizing the role of calcification in hair loss. It's not as simple as DHT=hair loss ubt DHT is definitely involved somehow otherwise 5AR inhibitors such as finasteride and dutasteride wouldn't be so effective. The best explanation of the bulletpoints you raise here is that DHT is somehow up stream of calcification and so by lowering DHT you also lower calcification but unfortunately there are currently no drugs that could realistically target the calcification. If there was I think we would have a good shot at full regrowth.