This is perhaps the most exciting new hair loss treatment in development. Currently in Phase 3 clinical trials, pyrilutamide (KX-826) is very close to becoming the first FDA-approved treatment for androgenetic alopecia in decades.
HMI-115 is a human monoclonal antibody drug being developed by Chinese company Hope Medicine for the treatment of androgenetic alopecia (male and female pattern hair loss).
In November 2021, Hope Medicine received FDA approval to start Phase 2 clinical trials of HMI-115 for androgenetic alopecia. In 2020, the FDA also approved Phase 2 trials of the same drug for endometriosis. Phase 2 clinical trials of HMI-115 for hair loss are due to begin in the USA soon.
In Australia, Phase 1 trials are currently underway. The trial is due to last 6 months, with 20 participants receiving injections every 2 weeks (12 injections total).
Since November, one of the participants in this Phase 1 Australian trial – a 37 year old man with the Reddit username moeman32 – has been posting some details of his experience to Reddit.
Dihydrotestosterone (DHT): it’s been blamed as the cause of hair loss ever since Dr. James Hamilton’s pioneering research in the 1940s. Yet despite Hamilton himself casting doubt on this theory, mainstream medicine has left this hypothesis mostly unchallenged. And while there is good evidence to support the link between DHT and hair loss, there are a number of problems with this explanation. So is DHT really the cause of hair loss? Or is it time for a new theory? Continue reading DHT and Hair Loss: Is It Really The Main Cause?
Propecia, the 1mg finasteride pill approved by the FDA to treat hair loss, may be far stronger than necessary. Numerous studies have shown doses as low as 0.2mg reduce DHT by the same amount as the prescribed 1mg tablet. So is such a high dose necessary to prevent hair loss? Is there a lower risk of side effects when taking a lower dose? In this article we’ll take a look at what the optimal finasteride dose for hair loss prevention is.
Perhaps as a result of today’s selfie-taking, image-obsessed culture, more and more men – and women – are using anabolic steroids to achieve the perfect body. But for many, this can have the unwanted side effect of increased hair loss. So can this be avoided? Which compounds are harshest on hair? Here’s how to prevent hair loss from steroids.
Ever wondered why it’s mostly men who go bald? Testosterone, the male hormone, gets converted to dihydrotestosterone (DHT), which binds to the hair follicle, causing it to shrink. Two drugs are medically approved to lower levels of this hormone, but which is the best hair loss treatment? finasteride or dutasteride? Propecia or Avodart? Continue reading Finasteride or Dutasteride for Hair Loss?
Propecia (finasteride 1mg) has been around since 1997. It’s the most popular hair loss drug worldwide and is taken by millions of sufferers worldwide. However, it doesn’t have the best reputation, with many users reporting erectile dysfunction and other sexual side effects. Many more are justifiably afraid of using Propecia for fear of suffering the same unwanted effects. Now, though, an alternative method of administering the drug promises to deliver the same benefits without the risks. So is topical finasteride a safer alternative to Propecia? Continue reading Topical Finasteride: A Safer Alternative to Propecia?
Finasteride, the active chemical in Propecia and Proscar, is commonly prescribed by doctors to treat male pattern baldness. Do a quick Google search, though, and you’ll quickly find horror stories from people who’ve used it as a hair loss treatment only to suffer terrible side effects – some irreversible. At the same time, numerous trials and studies have shown it to be very safe. So what exactly is the truth about finasteride side effects? Continue reading The Truth About Finasteride Side Effects